Small Molecule Prefilled Syringes; Alternatives to Other Dosage Forms, Such As Tablets and Capsules

Small molecule prefilled syringes are pharmaceutical preparations of small molecule drugs that are sold in prefilled syringes. Prefilled syringes are widely used to package injectable drugs and diluents. Some categories of drugs packaged in prefilled syringes are blood stimulants, vaccines, therapeutic proteins, interferons, erythroproteins, and rheumatoid arthritis. Prefilled provides greater patient safety by reducing the possibility of unintentional exposure to needle sticks and toxic products that can occur when taking medication from vials.

Moreover, small molecule prefilled syringes help reduce dosing errors and increase the patient compliance. Prefilled syringes are stored in refrigerator with the needle pointing up to prevent insulin from blocking the needle opening. Syringes filled with one type of insulin are kept for about a month. Prefilled syringes are used to delivery various drug categories. Drugs categories that belongs to cardiovascular, neurology, analgesics, and adjuvants are usually offered in small molecule prefilled syringes.

Thus, there is an increasing demand for small molecule prefilled syringes, owing to the wide availability of both generic and branded prefilled syringes and advantages over conventional dosage forms (instant effect), such as capsules and tablets. A prefilled syringe is a single-dose packet of vaccine to which a needle has been fixed by the manufacturer. UK and Germany have the largest market share prefilled syringes market in Europe. In January 2019, SCHOTT AG, Germany, launched customizable prefilled glass syringes in India.

Moreover, in September 2019, Schreiner MediPharm, a Germany-based provider of specialty pharmaceutical labeling products, developed a new tamper-evident security concept for luer-lock syringes. Compared to capsules and tablets, small molecule prefilled syringes have faster therapeutic action, as drug directly enters into the bloodstream. Prefilled syringes help reduce dosage errors and incidences of needle-stick injuries. It is pre-filled syringe or a disposable syringe that is already loaded with the substance to be injected.